Generic substitution: a need for clarification

Clarification regarding generic substitution for psychotropic drugs.

Catatonia : Need for Clarification

in life and beliefs should be considered at par with the functional variables. Thus how a patient judges the outcome and how the outcomes influences the health related quality of life is as important as clinician's judgement of prognosis. Hence considering a high prevalence (25%) of depression amongst the cancer patients we feel the presence of a psychiatrist, psychoanalyst alongwith the surgeo...

'Locked rehabilitation': a need for clarification.

Recently, the term 'locked rehabilitation' has spread from commissioning to now also clinical parlance. This is without any clear service description or category of patient which this service manages. Differences between this new term and an established definition of low secure services are examined and reasons for the introduction of this terminology are discussed. This is contextualised withi...

Generic substitution: issues for problematic drugs.

The methodology and criteria for bioequivalence testing have been firmly established by the Food and Drug Administration (FDA). For certain drugs with a narrow therapeutic index (e.g., digoxin, levothyroxine, warfarin), generic substitution may not be advisable or even allowable, depending on the substitution laws of individual states. Digoxin and levothyroxine tablets are examples of drugs for...

Antiepileptic drugs: the drawbacks of generic substitution.

The need to curb the rising costs of health care has led policy-makers in many countries to consider widespread generic substitution of brand-name drugs as an eff ective means to cut costs. For example, on January 5, 2010, the NHS in England began a 3-month consultation to seek views on plans to automatically substitute branded drugs with generic versions in primary care. However, doctors, pati...